ONE-STEP SYNTHETIC OFP-TERT-BUTYLCALIX[4]ARENE DERIVATIVE VIA DIRECT BENZOYLATION: MECHANISM REACTION STUDIES
نویسندگان
چکیده
The aim of research the synthesis 5,11,17,23-tetra(t-butyl)-25-monohydroxy-26,27,28-tribenzoyloxycalix[4]arene (TBMTCA) material were by one-step synthesized benzoylation reaction 5,11,17,23-tetra(t-butyl)-25,26,27,28-tetrahydroxycalix[4]arene (TBCA) and benzoyl chloride is (1: 3,7) mol refluxing 3 hours at room temperature predicted mechanism models. product was carried out means FTIR 1H-NMR spectroscopy. results of5,11,17,23-tetra(t-butyl)-25-monohydroxy-26,27,28-tribenzoyloxycalix[4]arene (TBMTCA)synthesized light yellow crystalline having melting point 306-3090C in 90,2 % yields.
منابع مشابه
Electrosynthesis of Clozapine Drug Derivative via an EC Electrochemical Mechanism
The fact that oxidation, as one of the main routes of phase I metabolism of drugs, follows by conjugation reactions, and also formation of nitrenium ion as one of the clozapine oxidation products, directed us to investigate the oxidation of clozapine (CLZ) in the presence of nucleophile. The oxidation of clozapine (CLZ) has been studied on a glassy carbon electrode in the absence and presence o...
متن کاملOne-Pot Synthesis of a New Imidazole-5-Carboxylic Acid Derivative via Heterocyclization Reaction
From few decades, fused heterocyclic chemistry has occupied a prominent place in Medicinal Chemistry. Moreover, fused imidazole systems have attracted the researcher’s interest due to their natural occurrence and significant medicinal applications [1-3]. Additionally, the benzimidazole derivatives are the bioisosters of natural nucleotides, which can interact easily with the macromolecules (pro...
متن کاملDirect transformation of arylpropynes to acrylamides via a three-step tandem reaction.
A novel and metal-free acrylamides formation between arylpropynes and hydroxylamine hydrochloride through sp(3) C-H and C-C bond cleavage has been achieved with DDQ as an oxidant. The mechanistic study shows that the acrylamides are formed through a three-step tandem sequence, including cross-dehydrogenative-coupling (CDC) reaction, aza-Meyer-Schuster rearrangement and Beckmann rearrangement.
متن کاملSynthetic Studies on Tricyclic Diterpenoids: Direct Allylic Amination Reaction of Isopimaric Acid Derivatives†
A selective synthesis of 7- or 14-nitrogen containing tricyclic diterpenoids was completed according to a strategy in which the key step was the catalyzed direct allylic amination of methyl 14α-hydroxy-15,16-dihydroisopimarate with a wide variety of nitrogenated nucleophiles. It was revealed that the selectivity of the reaction depends on the nature of nucleophile. The catalyzed reaction of the...
متن کاملEfficient hydrogen evolution in transition metal dichalcogenides via a simple one-step hydrazine reaction
Hydrogen evolution reaction is catalysed efficiently with precious metals, such as platinum; however, transition metal dichalcogenides have recently emerged as a promising class of materials for electrocatalysis, but these materials still have low activity and durability when compared with precious metals. Here we report a simple one-step scalable approach, where MoOx/MoS2 core-shell nanowires ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International journal of advanced research
سال: 2022
ISSN: ['2707-7802', '2707-7810']
DOI: https://doi.org/10.21474/ijar01/15659